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a Facial Infiltrating Lipomatosis community

• Articles about Facial Infiltrating Lipomatosis - FIL

• Articles about PIK3CA Related Overgrowth Spectrum - PROS

• Study participation opportunities

• PROS websites

• Clinical trials

• Blogs by WonderFIL smiles members

• Other PROS patient organizations



Articles about Facial Infiltrating Lipomatosis - FIL

1983 - Congenital Infiltrating Lipomatosis of the Face: Clinicopathologic Evaluation and Treatment

1989 - CONGENITAL INFILTRATING LIPOMATOSIS

2004 - Congenital Infiltrating Lipomatosis of the Face and Neck

2009 - Case Report Congenital infiltrating lipomatosis

2010 - Facial infiltrating lipomatosis

2011 - Facial infiltrating lipomatosis: A case report and review of literature

2012 - Congenital diffuse infiltrating facial lipomatosis

2012 - Case Report Congenital infiltrating lipomatosis

2013 - Infiltrating lipomatosis of the face: A case series

2014 - PIK3CA activating mutations in facial infiltrating lipomatosis

2015 - Congenital infiltrating lipomatosis of face: Case report and review of literature

2015 - PIK3CA-Related Overgrowth Spectrum (PROS): Diagnostic and Testing Eligibility Criteria, Differential Diagnosis, and Evaluation

2017 - Congenital Infiltrating Lipomatosis of the Face: Case Report With Presentation of a New Multistep Surgical Approach.

2017 - Somatic PIK3CA mutations are present in multiple tissues of facial infiltrating lipomatosis.

2018 - Congenital Infiltrating Lipomatosis of the Face: Case Report and Literature Review


Articles about PIK3CA Related Overgrowth Spectrum - PROS

2015 - Sirolimus Effect on Hypertrophic Syndromes Related Gene PIK3CA

2017 - ArQule Announces First Patient Dosed in Company Sponsored Phase 1/2 Trial of AKT Inhibitor, ARQ 092, for Rare Overgrowth Diseases

2017 - Molecular diagnosis of PIK3CA-related overgrowth spectrum (PROS) in 162 patients and recommendations for genetic testing

2018 - Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

2018 - Certain skin conditions signal potential overgrowth disorder

2018 - Understanding activating PIK3CA mutations in human disease

2018 - PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations

2018 - Syndrome d "elephant man": enfin un espoir de traitement

2018 - Targeted therapy in patients with PIK3CA-related overgrowth syndrome

2018 - Lessons for cancer drug treatment from tackling a non-cancerous overgrowth syndrome


PROS Related websites

PROS Spectrum - Novartis created website about PROS geared towards physicians


Study participation opportunities

RudyStudy

Segmental Overgrowth Study


Clinical trials

Study of ARQ 092 in Patients With Overgrowth Diseases and/or Vascular Anomalies (MOSAIC)

Trial of Taselisib in Overgrowth (TOTEM)

Study of Sirolimus Therapy for Segmental Overgrowth Caused by Somatic PI3K Activation


Blogs by WonderFIL smiles members

Ana Lucia's Smile

Josie's blog

Victor's Facebook page

Wilma's blog


Other PROS patient organizations

Facial Infiltrating Lipomatosis Illustration Woman
Facial Infiltrating Lipomatosis Illustration Girl
Facial Infiltrating Lipomatosis Illustration Male

Facial Infiltrating Lipomatosis and PROS related links

AIMP Italian Macrodactyly and PROS org
CLOVES Syndrome Community
CLOVES Syndrome Foundation
Klippel-Trenaunay Support Group
M-CM Network

This website is intended to connect families and people with Facial Infiltrating Lipomatosis (FIL), share experiences, provide information and support.

It is not intended for medical diagnostic use or to replace medical consultation. No images on this website may be used or reproduced.  

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