Links

Articles about relevant research

2015 - Sirolimus Effect on Hypertrophic Syndromes Related Gene PIK3CA (PROMISE)

2017 - ArQule Announces First Patient Dosed in Company Sponsored Phase 1/2 Trial of AKT Inhibitor, ARQ 092, for Rare Overgrowth Diseases

2017 - Gene Editing With CRISPR-Cas9

2018 - Understanding activating PIK3CA mutations in human disease

2018 - PI3K/mTOR inhibition promotes the regression of experimental vascular malformations driven by PIK3CA-activating mutations

! 2018 - Syndrome d "elephant man": enfin un espoir de traitement

! 2018 - Targeted therapy in patients with PIK3CA-related overgrowth syndrome

! 2018 - Lessons for cancer drug treatment from tackling a non-cancerous overgrowth syndrome


RudyStudy

Segmental Overgrowth Study

 

Clinical trials

Recruting - Study of ARQ 092 in Patients With Overgrowth Diseases and/or Vascular Anomalies

Recruting - Trial of Taselisib in Overgrowth (TOTEM)


Completed - Study of Sirolimus Therapy for Segmental Overgrowth Caused by Somatic PI3K Activation


Articles about FIL

1983 - Congenital Infiltrating Lipomatosis of the Face: Clinicopathologic Evaluation and Treatment

1989 - CONGENITAL INFILTRATING LIPOMATOSIS

2004 - Congenital Infiltrating Lipomatosis of the Face and Neck

2009 - Case Report Congenital infiltrating lipomatosis

2010 - Facial infiltrating lipomatosis

2010 - Congenital infiltrating lipomatosis of the face with ipsilateral hemimegalencephaly, band heterotopia, and hypertrophy of brainstem and cerebellum

2011 - Facial infiltrating lipomatosis: A case report and review of literature

2012 - Congenital diffuse infiltrating facial lipomatosis

2012 - Case Report Congenital infiltrating lipomatosis

2013 - Infiltrating lipomatosis of the face: A case series

2014 - PIK3CA activating mutations in facial infiltrating lipomatosis

2015 - Congenital infiltrating lipomatosis of face: Case report and review of literature

2015 - PIK3CA-Related Overgrowth Spectrum (PROS): Diagnostic and Testing Eligibility Criteria, Differential Diagnosis, and Evaluation

2017 - Congenital Infiltrating Lipomatosis of the Face: Case Report With Presentation of a New Multistep Surgical Approach.

2017 - Somatic PIK3CA mutations are present in multiple tissues of facial infiltrating lipomatosis.

2018 - Congenital Infiltrating Lipomatosis of the Face: Case Report and Literature Review.


Articles about PROS (PIK3CA Related Overgrowth Spectrum)

2017 - Molecular diagnosis of PIK3CA-related overgrowth spectrum (PROS) in 162 patients and recommendations for genetic testing

2018 - Cancer-Associated PIK3CA Mutations in Overgrowth Disorders

2018 - Certain skin conditions signal potential overgrowth disorder


Blogs by members of the WonderFIL smiles community

http://wilmawestenberg.nl

http://josiebeangrace.blogspot.no

http://www.lasonrisadeanalucia.com


Facebook pages by members of the WonderFIL smiles community

https://www.facebook.com/lasonrisadeanalucia/

https://www.facebook.com/VictorPadillasPageofHope/


Websites to other PROS conditions

www.gopi3ks.com

www.clovessyndrome.org

www.m-cm.net

https://k-t.org

Facial Infiltrating Lipomatosis
Facial Infiltrating Lipomatosis
Facial Infiltrating Lipomatosis
Facial Infiltrating Lipomatosis

This website is intended to connect families and people with the condition, share experiences, provide information and support. The website is not intended for medical diagnostic use or to replace medical consultation.

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